1) The first general election after the formation  of kerala state was held in

2) Who is the founder of Thruvithamkoor Ezhava Mahasbha

3) Who consecrated mirror (Kannadi Prathishta) for the first time in South India

4) First women Judge in supreme court of india

5) Who is the Author of Moksha pradheepam?

6) Dheenabandhu Sarvajanika Sabha was found by

7) Name the Malayali political leader whose statue is installed in Indian parliament?

8) The article 21 of Indian Constitution entries:

9) The mugal Architecture is a blending of

10) Wto led th6 Anri-British stng3le in Kiiioor?

(A) Rani Larmi Bai

(B) BeegaE Ilazat Mah,l

(c) Moulsvi AIEeduUah

(D) RdnichaM@da

VNTR analysis involves:
A) Analyzing specific loci for 2 base repeating units usually less than 100 bp
in size
B) Analyzing specific loci for 2 to 4 bp repeating units
C) PCR amplification of specific genes
D) Cutting DNA with restriction enzyme and analyzing the banding pattern of
fragments

Glomerular filtrate becomes increasingly hypertonic in
A) Proximal convolution                       B) Distal convolution
C) Ascending limb                                  D) Descending limb

Silviculture deals with
A) Multiplication of silk worm
B) Extraction of silver from plants
C) Cultivation of forest trees
D) Study of social forestry

About a fully turgid cell which among the following statement is correct?
A) D.P.D is maximum
B) D.P.D will be equal to O.P
C) Osmotic pressure equals with that of Turgor pressure
D) Osmotic pressure is maximum

In case of lac operon when disaccharide enters the cell:
A) it binds to the bound-repressor-to-the-operator and the structural genes are
transcribed because the RNA polymerase can recognize and bind the
transcription initiation site
B) it binds to the repressor and structural genes are transcribed because the
repressor has an altered conformation, is inactivated and does not bind the
operator.
C) the membrane protein interacts with the operator and the RNA polymerase
can recognize the transcription initiation site
D) the membrane protein has an altered conformation and does not interact
with the operator, thus leading to the transcription of the structural genes

Which is an esterolytic enzyme that hydrolyzes glycerophospholipids at the sn-2
position of the glycerol back bone?
A) PLA2                         B) ADH
C) Estrogen                   D) Hyaluronidase

The principal site of peptide neurohormone biosynthesis is
A) Nucleus                      B) Rough ER
C) Dendrite                     D) Post synaptic density

All of the following apply to the concept of the extinction vortex except:
A) Populations of the species entering it are small.
B) It is a concept developed by conservation biologists who adopt the "small
population approach."
C) The genetic variation of the species' population decreases.
D) The key factor driving the extinction vortex is intraspecific competition.

19) Polytene chromosomes in salivary glands of Drosophila are formed as a result of

i Endoduplication
ii Duplication without separation
iii Replication of DNA without cell division

A) i & ii only                               B) i & iii only
C) ii & iii only                            D) i, ii & iii

Geraniol is secreted from
A) Queen honey bee                      B) Worker bee
C) Termite                                       D) Male honey bee

Which aspect of mitosis is affected by colchicine in inducing polyploidy?
A) DNA duplication                        B) Chromosome doubling
C) Spindle formation                     D) Formation of cell plate

When two or more subliminal stimulus are given to a muscle fibre in quick
succession the muscle fibre contracts. The phenomenon is
A) Tetanus                    B) Summation
C) Tonus                       D) Tension

Which of the following is common to blood plasma and serum?
A) Plasma protein                     B) Water
C) Calcium ions                        D) Fibrinogen and platelets

Fragile X-associated mental retardation syndrome
A) Is transmitted from father to son
B) Affects females and males equally
C) 20% of carrier males show no sign of the syndrome
D) Involves a nonrepetitive segment of DNA

Which of the following is first digested in the stomach?
A) Carbohydrate                     B) Fat
C) Protein                                 D) Nucleic acid

Eggs of Branchiostoma come under which classification of egg based on the
amount of yolk?
A) Microlecithal egg                        B) Mesolecithal egg
C) Megalecithal egg                         D) None of the above

In clinical trials, control groups of individuals who receive a safe but noneffective
treatment instead of the drug being studied are being given:
A) A double-blind trial                         B) Stem cells
C) A placebo                                           D) None of these

Gull’s disease is due to the faulty working of
A) Pituitary gland                            B) Adrenal gland
C) Gonads                                         D) Thyroid gland

Inheritance of Poky in Neurospora crassa is an example of
A) Plastid inheritance                     B) Infective inheritance
C) Plasmid inheritance                  D) Mitochondrial inheritance

Viral disease Trachoma is related with
A) Eyes                       B) Skin
C) Liver                      D) Muscle

A hapten is a nonimmunogenic small protein. Which of the following statements
best describes haptens?
A) Haptens activate T cells
B) Penicillin is a hapten
C) Haptens do not react with specific antibody
D) Haptens bind the major histocompatibility complex (MHC)

In humans, Philadelphia chromosome results from the reciprocal translocation
between chromosome numbers
A) 10 and 20                       B) 9 and 20
C) 9 and 22                          D) 3 and 11

Certain species of birds shows variation in beak size only when they are
sympatric. This is an example of
A) Character displacement             B) Natural selection
C) Ecological variance                     D) Mutation

Which of the following is a vertebrate organism?
A) Cuttle fish                        B) Cray fish
C) Globe fish                        D) Devil fish

When the body cavity arises from the archenteron of embryo, the cavity is termed
as
A) Coelom                 B) Pseudocoelom
C) Haemocoel           D) Blastocoels

In normal human males, the male determining genes on the Y chromosomes
which organizes the developing gonad into a testis instead of ovary
A) DDS                      B) SRVX
C) SRY                       D) None of the above

A geographically localized group of individuals of the same kind at a particular
time represents a
A) Tribe                                   B) Species
C) Community                       D) Population

If a dwarf pea plant was treated with giberellic acid, it grew tall as a pure tall
plant. If it is crossed with a pure tall plant, then the phenotype ratio of F1 progeny
will be
A) All dwarf                                    B) 50% tall and 50% dwarf
C) 75% tall and 25% dwarf          D) All tall

How many bacteria are produced in four hours if a bacterium divides once in half
an hour?
A) 8                B) 64                    C) 128                 D) 256

Analysis of a patient’s stool reveals small structures resembling rice grains;
microscopic examination shows these to be proglottids. The most likely organism
in this patient’s stool is
A) Enterobius vermicularis                   B) Ascaris lumbricoides
C) Necator americanus                          D) Taenia saginata

Holandric genes are present in
A) Autosomes                              B) X chromosomes
C) Y chromosomes                     D) None of the above

All of the following are true of antigen EXCEPT
A) They contain epitopes                    B) They contain antigenic determinants
C) They contain paratopes                 D) They can elicit immune response

The substitution of valine for glutamate at position 6 on the two β chains in sickle
cell hemoglobin causes which of the following?
A) Increased electrophoretic mobility at pH 7.0
B) Increased solubility of deoxyhemoglobin
C) Decreased polymerization of deoxyhemoglobin
D) Unchanged primary structure

Among the following which is not an assumption of Hardy-Weinberg rule?
A) No natural selection
B) Random mating
C) Small population size
D) No mutation

If the insulin gene located on Chromosome II is switched on all the time, the
blood sugar in the blood and other organs will be devastated within a short time,
so gene expression is regulated by on-off switches and such genes are called
A) Constitutive genes                       B) Housekeeping genes
C) Inducible genes                            D) Selfish genes

Tendons connect
A) Bone to bone                                 B) Bone to muscle
C) Muscle to muscle                          D) Muscle to nerve

T/t genes control the character ‘height’. In a population of 500 individuals there
are 400 T allele. How many ‘t’ allele will be present in that population?
A) 600                B) 1000                   C) 400                     D) 1200

These are specialized fat body cells which store Potassium-urate and uric acid as
excretory waste
A) Calloblast cells              B) Trichogen cells
C) Peptic cells                      D) Urate cells

Duchene muscular dystrophy is caused by the presence of:
A) A defective gene in X-chromosome
B) An extra 18th chromosome
C) Two X-chromosomes and one Y-chromosome in an individual
D) An extra 21st chromosome

Human respiration follows
A) Boyle’s law                       B) Beer’s law
C) Allan’s law                        D) Charles law

Gram-negative and gram-positive bacteria possess which one of the
following structures?
A) Peptidoglycan                              B) Matrix protein
C) Pili                                                 D) Flagella

The small part of chromosome arm beyond secondary constriction is called
A) Kinetochore                  B) Satellite
C) Centromere                  D) Telomere

Number of mitotic divisions required to produce 128 cells from a single cell is
A) 7                B) 14             C) 8                         D) 16

In melandrium the sex determination type is
A) XX – XY type B) XX – XO type
C) ZZ – ZW type D) XY – XO type

The latest and most effective therapy for AIDS patients includes azidothymidine
(AZT), dideoxyinosine (DDI), and saquinavir or similar agents. Use of these three
drugs would inhibit which of the following viral processes?
A) RNase, DNase
B) gp 120 formation
C) p 24 antibody expression
D) Reverse transcriptase, protease

Nerve cells of retina are
A) Bipolar                   B) Multipolar
C) Unipolar                D) Apolar

In which microscopic technique use out-of-phase light waves to produce
differences in contrast are combined with two beams of light travelling close
together, which create even more contrast, especially at the edge of the structures
A) Bright field microscopy
B) Dark field microscopy
C) Phase contrast microscopy
D) Differential interference contrast microscopy

Growth due to the activity of reserve cells is
A) Accretionary growth                  B) Multiplicative growth
C) Auxentic growth                         D) Exponential growth

Which GTPase regulates intracellular transport in mammalian cell through
A) Rab              B) Ran                 C) Ras                D) Rho

FAD participated as the hydrogen acceptor in Krebs cycle during the conversion
of
A) Succinyl co-A to succinic acid
B) Fumaric acid to malic acid
C) Succinic acid to fumaric acid
D) Iso-citric acid to oxalosuccinic acid

Hamburger phenomenon is associated with
A) Transportation of oxygen                        B) Transportation of carbon dioxide
C) Transportation of hormones                   D) None of the above

In F2 progeny of dihybrid cross, the expected genotypic proportion of individuals,
homologous for both factor pairs will be
A) 1/16               B) 2/16      C) 3/16             D) 6/16

Respiratory system of majority of adult insects consists of
A) Gills                                                  B) Bronchial apparatus
C) Tracheal system                             D) Book lungs

An endocrine gland with ectodermal and mesodermal origin?
A) Adrenal                            B) Epiphysis
C) Hypophysis                     D) Thyroid

Immunoglobulin not present in human colostrums
A) IgG       B) IgA     C) IgM     D) IgE

Otoliths are made of
A) Calcium carbonate                  B) Phosphate
C) Both A and B                            D) None of these

The gene for green fluorescent protein (GFP), a commonly used reporter gene,
was cloned from:
A) Vibrio cholera                       B) Aequorea victoria
C) Susdomesticus                     D) Daniorerio

What is the specificity of the Clostripain protease?
A) It cleave after Arg. residues              B) It cleave after His. residues
C) It cleave after Lys. residues               D) None of the above

The statistical test involved to verify whether the results in a breeding experiment
follow Mendelian ratio:
A) ANOVA                                   B) t-test
C) Regression analysis              D) Chi-square

Regulatory T lymphocytes are characterized by possession of surface markers
A) CD 4 CD 8                  B) CD 4 CD 28
C) CD 4 CD 25                 D) CD 4 CD 40

With the help of isotopes, Hershey and Chase found out in bacteriophage, the
genetic material is DNA, identify the isotopes used?
A) P32 and S35                    B) P35 and S32
C) P35 and S30                    D) P32 and S30

If a normal woman marries a colourblind man
A) All their children will be colourblind
B) All their sons will be colorblind but the daughters will be normal
C) All the children will be normal
D) All daughters will be colourblind and sons will be normal

Which of the following layer is the outermost one of the skin with dead cells?
A) Stratum lucidum                       B) Stratum corneum
C) Stratum spinosum                     D) Stratum granulosum

Phospholipid with choline as nitrogen group is called
A) Cutin               B) Lecithin
C) Lignin               D) Suberin

Which of the following transcription factors play a major role in inflammatory
signaling in cells of the vertebrate immune system?
A) STAT                          B) NF-kappa B
C) CREB                         D) SP-1

The type of placenta in primates is
A) Diffuse                             B) Zonary
C) Cotyledonary                  D) Discoid

A woman who married her first cousin wants to know the risk of having a child
with cystic fibrosis because her grandmother, who is also her husband’ s
grandmother, died of cystic fibrosis. The chances of her risk is
A) 1/8                     B) 1/16                C) 1/60                D) 1/120

Two examples of substrate level phosphorylation in EM pathway of glucose
metabolism are in the reactions of
A) 1,3 bisphosphoglycerate and phosphoenol pyruvate
B) Glucose-6 phosphate and Fructo-6-phosphate
C) 3 phosphoglyceraldehyde and phosphoenolpyruvate
D) 1, 3 diphosphoglycerate and 2-phosphoglycerate

Puffs of salivary gland chromosomes are the site for
A) Protein synthesis       B) DNA synthesis
C) RNA synthesis           D) Replication of DNA

The origin of heart beats and their conduction is represented in the pathway
A) AVN - Bundle of His – SAN - Network of Purkinje fibers
B) Network of Purkinje fibers – AVN – SAN - Bundle of His
C) AVN – SAN - Bundle of His - Network of Purkinje fibers
D) SAN - AVN - Bundle of His - Network of Purkinje fibers