HUMAN GENOME PROJECT Mock Test

🟥 HUMAN GENOME PROJECT

🟥 QUESTIONS :25

🟥 TIME : 20 MINS

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1) The locations in human genome which differ by a single base difference is known as

A) - Single nucleotide mutation -

B) Single nucleotide polymorphism

C) - RFLP -

D) Single nucleotide polymorphogensis

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2)

the major approaches used in HGP for identifying genes were
-

A) BLAST -

B) Expressed sequence tags -

C) Sequence annotation

D) - B and C

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3)

: Which of the following were not used in HGP?
-

A) Vectors like BAC and Y -

B) Hosts like plants and animals -

C) Protein sequencers

D) - DNA sequencers

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4)

Number of genes in chromosome 1 is
-

A) 2698 -

B) 2968 -

C) 2689

D) 2986

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Name the largest known gene in
human

5)

A) Dystrophin Gene

B) Y Gene

C) Gene Dideoxy Gene

D) BAC

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6) HGP associated with new area of biology is

A) - Biotechnology -

B) Computational biology

C) - Bioinformatics -

D) All the above

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7) Automated sequencing is defined as _____

A) Chain termination sequencing

B) Radio labeled sequencing

C) Real time fluorescence sequencing

D) Pyrosequencing

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8)

What are the methodology adopted in HGP
-

A) Expressed sequence tags - -

B) Sequence annotation -

C) Sequence delivery

D) A& B

E) - A & C

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9) Human genome project started in the year of

A) . 1992

B) . 1990

C) . 1992

D) 1994

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10) The first automated DNA sequencer, invented

A) Francis Ckrick

B) Charggaff

C) Alec Jeffery

D) Lloyd M. Smith

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11) Which of the following methodology is used to identify all the genes that are expressed as RNA in Human Genome Project (HGP)?

A) Sequence Annotation

B) Expressed Sequence Tags

C) Karyotyping

D) Ammonification

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12)

According to HGP , genetic similarity between all humans is
-

A) 90%, -

B) 95% -

C) 99.9%

D) - 99.5%

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13) Which of the following is a suitable host for the process of cloning in Human Genome Project (HGP)?

A) Virus

B) All types of fungi

C) Protozoan

D) Bacteria

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14)

The first draft of HGP was published in 2001 in the journal ]
-

A) Science

B) - Cell -

C) Nature

D) - Plos Biology

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15)

The private company involved in human genome sequencing in parallel with HGP was
-

A) Roche -

B) Gilead -

C) Celera -

D) Genentech

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16) The largest gene in humans is

A) - Titin

B) - Dystrophin -

C) Insulin -

D) Phosphofructokinase

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17)

The locations in human genome which differ by a single base difference is known as
-

A) Single nucleotide mutation -

B) Single nucleotide polymorphism -

C) RFLP

D) - Single nucleotide polymorphogensis

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18) . The determination of genes involved in complex diseases will be greatly helped by

A) DTP maps;

B) SNP maps;

C) DNP maps;

D) MCP maps.

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19) The number of SNPs has been identified which may be more than

A) 2 million;

B) 2.5 million;

C) 3 million;

D) 4 million. Ans. c.

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20) The estimated number of protein-coding genes ranges from

A) 30,000 to 40,000;

B) 35,000 to 42,000; ns. a.

C) 40,000 to 46,000;

D) 50,000 to 60,000.

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21)

The percentages of proteins encoded by human genes are derived from a total gene number
(

A) 26,282;

B) 26,292;

C) 26,322;

D) 26,383.

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22) Human genome project was completed in the year

A) - 2001

B) - 2002 -

C) 2003

D) - 2000

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23)

Which of the following is a suitable host for the process of cloning in Human Genome Project (HGP)?
a)

A) Virus

B) Protozoan

C) All types of fungi

D) Bacteria

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24) Which of the following is a suitable vector for the process of cloning in Human Genome Project (HGP)?

A) PAC (Protozoal Artificial Chromosomes)

B) FAC (Fungal Artificial Chromosomes)

C) YAC (Yeast Artificial Chromosomes)

D) VAC (Viral Artificial Chromosomes)

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25)

: Human Genome Project was initiated by
-

A) NIH & DOE

B) - NIH & EBI

C) - NIH & DDBJ

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