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ZOOLOGY Molecular Biology Mock Test 4

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108

ZOOLOGY Molecular Biology Mock Test 4

🟥 ZOOLOGY Molecular Biology Mock Test 4

🟥 QUESTIONS : 30

🟥 TIME : 30 Mins

1 / 30

1)

Which of these class lll promoter type resembles class ll
A. Type l
B. Type ll
C. Type lll
D. Type lV

2 / 30

2)

TFIIB can bond to a promoter element in the core promoter of eukaryotes, this element is
A. Inr
B. BRE
c. DPE
D. TATA

3 / 30

3)

TATA box in eukaryotes would be present in
A. Housekeeping genes
B. Developmentally regulated genes
C. Cytoskeletal genes like that for actin
D. Highly specialised genes

4 / 30

4)

Which would be an appropriate method to detect the core promoter region in a eukaryotic gene
A. Footprint
B. Sequencing
D. Linker scanning
D. S1 endonuclease

5 / 30

5)

Regulatory proteins turn transcription off through binding to a site rapidly at the front of the promotor and many times even overlaps the promoter , this site is
A. Regulatory site
B operator site
C. Suppressor site
D. Transcriptional control site

6 / 30

6)

Gene imprinting involves __
A. DNA methylation
B. DNA phosphorylation
C. DNA glycosylation
D. DNA oxidation

7 / 30

7)

Immunoglobulin enhancers are active in which of the following cell types ?
A. B lymphocyte
B. T lymphocyte
C. Macrophage
D. Megakaryocytes

8 / 30

8)

Enhancers that can function over very long distances known as
A. Cis acting enhancers
B. Trans acting enhancers
C. Transvection
D. Allosteric enhancer

9 / 30

9)

Which of the following increases gene expression as much as 200 fold?
A. TATA box
B. Insulator
C. Enhancer
D. CAAT box

10 / 30

10)

The most common form of gene expression regulation in both bacteria and eukaryotes is
A. Translational control
B. Transcriptional control
C. Post transcriptional control
D. Post translational control

11 / 30

11)

Eukaryotic entities
A. In the presence of a CAMP molecule it carries out protein synthesis
B.have operons assisting in gene expression
C. Transcription takes place in the nucleus and translation in the cytoplasm
D. Transcription occurs in the cytoplasm and translation in nucleus

12 / 30

12)

Which among the following is known as suicide enzyme
a.DNA alkyltransferase
b.O6 alkylguanine DNA alkyltransferase 1
c.O6 alkylguanine DNA alkyl transferase 2
D.Both b and c

13 / 30

13)

PCR is developed by
1.Maxam Gilbert
2.Kary Mullis
3.Sanger
4.Mc Carty

14 / 30

14)

During replication in E. Coli the unwinding of DNA is catalyzed by?
A)DNA Helicase
B)SSDNA binding protein
C)DNA topoisomerase
D)DNA polymerase

15 / 30

15) Which of the following genetic code shows ambiguity?

a) CGU
b) AUG
c) GAC
d) UGA

16 / 30

16)

During prokaryotic DNA replication the supercoiled DNA is relaxed by the enzyme
a) DNA ligase
b) DNA polimerase
c) Gyrase
d) Topoisomerase

17 / 30

17)

Which enzyme mediate the process of formation of amino acyl tRNA from tRNA
a) amino acetyl tRNA synthetase
b) amino acyl tRNA transferrase
c) aminoacyl tRNA synthetase
d) amino acetyl tRNA esterase

18 / 30

18)

Who first isolate DNA from Human cell?
a) James Watson
b) Fredrich Miecher
c) Mac Leord
d) MC carry

19 / 30

19)

Chargaff's rules were formulated in
a. 1949
b. 1944
c. 1928
d. 1903

20 / 30

20)

. A left handed DNA is
a. A DNA
b. Z DNA
c. B DNA
d. C DNA

21 / 30

21)

The double helix of DNA is stabilized by:
a. Base pairing
b. Base flipping
c. Base stacking
d. Both a & c

22 / 30

22)

Which one of the following is an artificial chromosome
A. YAC
B. BAC
C. Both A & B
D. Lambda phage chromosome

23 / 30

23)

Which one of the following transgenic organisms was used to develop the hepatitis B vaccine
A. Sheep
B. E. coli
C. Pig
D. Yeast

24 / 30

24)

what is true about type II restriction endonuclease
A.it does not require ATP to cut DNA
B it cut DNA at restriction site itself
C .eg Hind III
D . ALL OF THESE

25 / 30

25) What is true about M13 Phage vecters

A .It is a filamentous bacteriophage of E.coli contains single standard circular DNA of 7.2 kb

B .these vectors have a polylinker with the unique restriction enzyme sites in lac Z gene that compliments host
C. Both A and B
D none of these

26 / 30

26) What is true about lambda phage vectors

A. it is a temperate bacteriophage having genome size of 48.5 kb
B . Linear double standard molecule with single stranded complimentary end
C . Both A and B
D . none of this

27 / 30

27)

The following code codes for which of the amino acid respectively?
AUG and GUG
a) Phenylalanine, tyrosine
b) Methionine, valine
c) Methionine, alanine
d) Lysine, valine

28 / 30

28)

For eukaryotic gene transfer most efficiently used vectors are:
🔹BAC
🔹YAC
🔹both (a) and (b)
🔹PBR322

29 / 30

29) The first successful attempt in animal cloning was done in:

🔹Xenopus
🔹Rana
🔹Salamander
🔹Newt

30 / 30

30)

which of these RNAP s show structural similarities
a. Bacterial RNAP
b. Archeal RNAP
c. Eukaryotic RNAP 2
d. a&c
e. b&c

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